If you want an even textured meatloaf, and hey who doesn't, always user your hands to gently mix the ingredients. Using a spoon will cause the meatloaf to become too compact.
For a moister meatloaf, use soft bread crumbs instead of dry. To eliminate calories, substitute grated potato or carrots for a portion of the meat.
To enhance the flavor of meatloaf, substitute red wine or dark beer for the liquids.
Mix and mold into a loaf. Bake at 375 degrees for approx. 40 minutes
Other Suggestions:
Cut up an onion and potatoes and place in a baking dish with meatloaf. Halfway through cooking time, pour a can of diced or stewed tomatoes over meatloaf.